Adrenergic Receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline). Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. High levels of circulating epinephrine cause vasoconstriction. At lower levels of circulating epinephrine, β-adrenoreceptor stimulation dominates, producing vasodilation followed by decrease of peripheral vascular resistance.
Many cells possess these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system. The sympathetic nervous system is responsible for the fight-or-flight response, which includes dilating the pupils, increasing heart rate, mobilizing energy, and diverting blood flow from non-essential organs to skeletal muscle.
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Oxymetazoline hydrochloride is an α1 and α2 adrenergic receptor agonist.
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Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.
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Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
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Hytrin (terazosin) is an alpha-adrenergic blocker used to treat high blood pressure and enlarged prostate.
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Phentolamine Mesylate is a nonselective alpha-adrenergic antagonist with IC50 of 0.1 μM.
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Oxymetazoline hydrochloride is an α1 and α2 adrenergic receptor agonist.
More
-
Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.
More
-
Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
More
-
Hytrin (terazosin) is an alpha-adrenergic blocker used to treat high blood pressure and enlarged prostate.
More
-
Phentolamine Mesylate is a nonselective alpha-adrenergic antagonist with IC50 of 0.1 μM.
More
